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Safe and effective vaccine against Clostridium perfringens in poultry

A recombinant vaccine based on toxoids of NetB and alfatox fit for vaccination of chickens against Clostridium perfringens.

The vaccine consists of a combination of recombinant NetB and alpha-toxin, both detoxified.

C. perfringens infections in poultry may present as an acute clinical disease, with high mortality at 2 to 5 weeks of age, or in a subclinical form leading to reduced weight gain which costs the worldwide poultry industry 2 billion USD annually (or 0,05USD per bird)

Proof of concept in target species (Ross308 broilers)

Immunisation with NetB- and alpha-toxoid reduced lesion scores completely.  None of the animals vaccinated with a combination of NetB and CPA developed necrotic enteritis lesions after challenge.


We are looking for partners that are interested to market the vaccine and we are open to assist during the transfer of the technology and during the development phase.

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