📄 Recent paper in Vaccines journal
8 Nov 2022
Exploring Prime-Boost Vaccination Regimens with Different H1N1 Swine Inﬂuenza A Virus Strains and Vaccine Platforms 💉🦠
Previous swine influenza vaccination studies from the research group of Prof. Van Reeth demonstrated that prime-boost vaccination with antigenically distinct swine influenza inactivated vaccines can broaden the immune response and improve protection. In this study we aimed to further improve this heterologous prime-boost vaccination strategy by using a live viral pseudorabies vector vaccine as a priming vaccine, to stimulate
both local and systemic immune responses. We illustrated that intranasal vector vaccination followed by a heterologous inactivated vaccination results in a broader immune response and protection than two doses of matched inactivated vaccine.
Read the whole article in the attached pdf.