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📑 New paper by the group of Prof. Dr. Filip Van Immerseel in PLOS Pathogens on Clostridium perfringens

24 Sept 2024

🐓 Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens

The interaction between bacteria and the intestinal mucus is crucial during the early pathogenesis of many enteric diseases in mammals. A critical step in this process employed by both commensal and pathogenic bacteria focuses on the breakdown of the protective layer presented by the intestinal mucus by mucolytic enzymes.


This research focusses on the roles of ChiA and ChiB in bacterial proliferation and mucosal attachment, two processes leading to colonization and invasion of the gut.


📖Read the full text on: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012560

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