Looking for an academic partner for your discovery projects?
Looking for an academic partner for your discovery projects?
Ghent University offers a unique proposal: the collaboration between veterinarians, physicians and scientists from different disciplines present at Ghent University takes the research to a higher level and creates many opportunities for innovation. At our Faculty of Veterinary Medicine these innovations can be tested in our own facilities and on the target species.
Check what we can offer in these fields
Ghent University offers a unique proposal: the collaboration between veterinarians, physicians and scientists from different disciplines present at Ghent University takes the research to a higher level and creates many opportunities for innovation. At our Faculty of Veterinary Medicine these innovations can be tested in our own facilities and on the target species.
Check what we can offer in these fields
🔬 New Insights Into TIE2 Localization on Kidney Podocytes Using Correlative STED–FLIM Microscopy
9 Feb 2026
🔬Correlating Stimulated Emission Depletion Microscopy With Fluorescence Lifetime Imaging Microscopy to Study the TIE2 Protein on Kidney Glomerular Podocytes
A new study takes a fresh look at the long-debated question of whether the TIE2 receptor is present on podocytes 🧬👀. By combining STED super-resolution microscopy 🔍⚡ with FLIM ⏱️🌈, the team overcomes key challenges in membrane protein detection, including tissue autofluorescence and antibody specificity.
This complementary imaging approach confirms the presence of TIE2 on mouse podocytes 🐭🧫 and maps its subcellular localization to the cell surface facing Bowman’s space 📍—albeit at lower expression levels compared to endothelial cells.
Beyond resolving a biological debate 🧠💡, this work highlights the power of integrating STED and FLIM 🤝🔬 to study low-abundance proteins in complex tissues.
🚀📊 A methodological and biological advance with exciting implications for kidney research and vascular biology!
👇Read the full text here