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The RespiGroup focuses on development of better therapy, control and prevention for respiratory diseases of large animals to improve their health, performance and welfare. A key objective is to rationalize antimicrobial use for respiratory tract infections and cattle is the main species. The RespiGroup develops rapid diagnostic tools, for both laboratory and on farm use, and (data-driven) decision support tools for each step in the antimicrobial decision making chain for respiratory disease outbreaks, including personalization of treatment (precision medicine) and targeted control. Being at the crossroads of practice, veterinary clinics and scientific research, the RespiGroup is well-positioned to translate science into practice.