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PROVAXS is the coordinating center of a network of laboratories of the University of Ghent that unite their expertise in the development of veterinary and human vaccines, therapeutics and diagnostics
PROVAXS focuses on those projects and research results that respond to an urgent need in society or in the market and can lead to industrial applications. We can therefore rely on specific funds for valorization that are available at our University and on the continuous support of Technology Transfer, the central department at the University of Ghent that assists in the protection and licensing of our intellectual property and helps to build strategic alliances.
PROVAXS wants to facilitate the transfer of new technologies in the domain of veterinary and human vaccines, therapeutics and diagnostics that result from multidisciplinary research to a practical and/or industrial application, thus realising a return to fundamental research.
PROVAXS is an interface that, with attention for the quality of high-end scientific research, is open for the needs and demands of our industrial partners and offers them solutions and opportunities in a pro-active way.
PROVAXS offers a multidisciplinary environment for research and development directed towards technologies with practical applications in industry
PROVAXS offers expertise in mucosal immunology, pathogen-host interactions of viruses and parasites, biomarkers of infections, immune response and immune diseases, related diagnostics, formulations for drugs and vaccines
PROVAXS can be your gateway to participation in a network of high-quality R&D in various research programs at national and international level
Via partnering PROVAXS can offer you access to gap-funding, an extra tool to stimulate and accelerate valorization of new technologies
PROVAXS joins the forces of laboratories of four different faculties of the University of Ghent
Faculty of Veterinary Medicine : Department of Virology, Parasitology and Immunology, Laboratory of Bacteriology
Faculty of Medicine and Health Sciences : Centre for Vaccinology, Department of Rheumatology, Centre for Cllinical Immunology and Allergy
Faculty of Bioscience Engineering : Laboratory for Immunology and Animal Biotechnology, Laboratory for Biochemistry and Molecular Cytology
Faculty of Pharmacy : Laboratory of Pharmaceutical Technology, Laboratory of Pharmaceutical Biotechnology, Laboratory of General Biochemistry and Physical Pharmacy
In the Laboratory of Virology, the research is focused on the animal, cellular and molecular pathogenesis of viruses, with a special emphasis on viruses that have developed strategies to escape from the host's immune response.
Projects are focused on the following topics :
Website
Besides routine DNA typing for the department of justice, our lab performs research in the field of DNA fingerprinting for optimising and improvement of the procedures. We created already our own multiplex of four STR loci and investigated the influence of dactyloscopic powders on DNA analysis.
At this moment we are investigating the use of immunomagnetic beads to purify and isolate specific cell types from mixed forensic samples. This way sperm cells could be isolated before DNA extraction avoiding time-consuming differential DNA extraction. Forensic mixtures in general can be avoided when this mixed sample consists of different cell types.
Proteomics is defined as the large-scale characterisation of the entire protein complement of a cell line, tissue and organism. It provides us with a more global and integrated view of biology by studying all the proteins of a cell rather than each one individually. With the completion of the sequencing of several genomes it became clear that a lot of information could not be obtained by studying genes alone. It is impossible to elucidate mechanisms of disease, ageing and effects of the environment solely by studying the genome. Proteomics can provide us with a powerful tool for studying and understanding disease mechanisms and can actively contribute to the search for new drug targets.
Because of their nature of pathology, rheumatoid diseases have and are still extensively studied and looked at from an immunological point of view. However, proteomics is catching up with them! We are currently looking at the proteome of several rheumatoid tissues of different rheumatoid diseases in order to find differences in the expressed protein patterns. This study will provide us a better insight in the pathology of these diseases.
The Laboratory of General Biochemistry and Physical Pharmacy hosts the Ghent Research Group on Nanopharmacy (GRCN).
Nanopharmacy aims at applying nanotechnology in drug therapy and medical diagnostics. Advanced drug delivery and medical diagnostics constitute the core disciplines of GRCN. Advanced drug delivery systems are nano-/micrometre sized delivery systems for biological therapeutic agents (like nucleic acids and proteins) which are much larger than classical drugs like for example aspirin.
The GRCN is a multidisciplinary research environment, including pharmacists, material engineers, cellular biologists and biophysics who build scientific and technical expertise between "nano" and pharmacy.
Our expertise focuses on the following areas :
With regard to DNA therapy the Laboratory of General Biochemistry and Physical Pharmacy evaluates the use of non viral carriers for DNA delivery. Such 'DNA particles' (which are between 50 and 500 nm in size) consist of DNA and cationic polymers or cationic lipids.
Our DNA delivery research is especially focused on the mobility and the stability of non-viral DNA particles in the extra- and intracellular matrix.
To better understand the cellular behavior of non viral gene DNA complexes, we evaluate the potentials of new biophysical (microscopy) techniques like fluorescence correlation spectroscopy, fluorescence recovery after photobleaching,...
We believe that, in order to obtain real breakthroughs in the design and the understanding of the behavior of the DNA particles in cells, there is an urgent need for advanced biophysical methods which allow to characterize the critical steps in cells that govern gene transfection.
By modern biophysical methods we study e.g. the intracellular release of the DNA from the carriers, the intracellular degradation of DNA, the mobility of naked DNA and DNA particles in the cytosol, the uptake of DNA by the nuclei,...
Pharmaceutical research aims to design drug delivery systems that respond to therapeutic needs. To correlate with our biological needs, precisely timed drug delivery is required. Precisely timed therapy could be improved by the use of 'programmable dosage forms' which deliver the drug at well defined times after e.g. intramuscular or subcutaneous injection.
The Laboratory of General Biochemistry and Physical Pharmacy aims to design 'exploding particles' for pulsed release of macromolecular therapeutics. The pulsed delivery concept we are investigating is based on the use of degradable hydrogels. A degradable gel is encapsulated in the interior of a micron sized capsule along with the drug of interest . At the time the polymer gel becomes a polymer solution the swelling pressure suddenly increases inside the capsule. This results in a rupture of the capsule followed by drug release.
The Laboratory of General Biochemistry and Physical Pharmacy is officially approved to perform analysis of pharmaceutical enzymes on behalf of the Belgian Ministry of Health.
The laboratory is also a member of the European Network of Official Medicines Control Laboratories (OMCL). It also performs analysis of pharmaceutical enzymes ordered by the pharmaceutical industry.
Our contract work especially deals with the physicochemical characterization of solutions and solids like:
Website
www.ugent.be/fw/biofys
To be updated
To be updated
The mission of the Laboratory of Veterinary Bacteriology and Mycology is to promote knowledge on veterinary bacteriology and mycology through education, research and public services.
The main research interests of the laboratory are :
1) host-pathogen interactions of veterinary and / or zoonotically important bacteria and fungi.
2) antimicrobial resistance in veterinary and / or zoonotically important bacteria and fungi.
Animal species used for research purposes: Pigs, poultry, pigeons, mice, gerbils, reptiles, amphibians.
The laboratory is approved for research activities with these animal species, meeting both ethical and biosafety requirements to perform infection experiments up to an L2 level, including GMOs. All infection experiments are carried out in A2 stables, adapted to meet all ethical and biosafety requirements.
Microorganisms:
1) Host-pathogen interaction studies: Salmonella (several serovars), Campylobacter jejuni, Helicobacter (several gastric and enterohepatic species), Clostridium perfringens, Batrachochytrium dendrobatidis, Aspergillus fumigatus, Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Staphylococcus aureus
2) Antimicrobial resistance: bacteria of veterinary and / or zoonotic importance (please inquire for specific taxa)
In vitro models:
1) Adhesion, invasion and cytotoxicity assays using several cell lines and primary cell cultures.
2) Determination of Minimal Inhibitory Concentrations (MIC) for various veterinary and / or zoonotically important bacteria.
3) Virulence gene expression of Salmonella.
In vivo models:
Pigs Salmonella:
Several infection models are used, inoculating 3 to 4 week-old piglets either with a single Salmonella strain or with multiple strains (mixed infection):
Poultry Salmonella:
Poultry Campylobacter jejuni:
Poultry Clostridium perfringens: reproduction of necrotic enteritis lesions
Pigeons Salmonella Typhimurium: reproduction of pigeon paratyphoid
Pigeons Aspergillus fumigatus: reproduction of avian aspergillosis
Gerbils and mice gastric Helicobacter species: reproduction of gastric lesions
Pigs Mycoplasma hyopneumoniae: reproduction of enzootic pneumonia
Reptiles Salmonella: persistent colonization
Pigs Actinobacillus pleuropneumoniae
Rabbits Staphylococcus aureus
PROVAXS wants to facilitate knowledge transfer activities and research collaboration with other research institutes and industrial companies.
Our Technology Offers describe technologies with clear practical applications that are part of our IP-portfolio.
R&D projects are an invitation to join us in early stage development programs that already showed a proof of concept but need some further exploratory research in order to define clear target applications in the market.
We also offer Tools and Test Models that you can use for screening and testing of the biological activity of your material.
We kindly invite you to examine if our technologies can match your company strategy and market needs and can be converted into useful products or services.
• The PRRS-virus can infect the cells via the natural route due to the presence of both sialoadhesin and CD163, the two receptors that are essential for binding, internalization and multiplication
• On average Sn+CD163 cells can produce PRRSV at titers of 1 log higher than in MARC-cells
• Multiple PRRSV-strains can be grown on the Sn+CD163 cells which offers flexibility in production (e.g. for multistrain registration)
• The cells can be used for QC or in a potency test to demonstrate structural and functional integrity of the PRRSV as long as it can bind and internalize
• Since the PRRS-virus can follow its natural route of infection no or little virus adaptation is expected
You can download a Technology Offer here.
Our technology enables you to check the antigenicity (efficacy) and safety of your inactivated viral vaccine in vitro
A quick and safe way to develop safe and effective viral vaccines against emerging diseases or new aggressive strains
Fully documented proof-of-concept study on a PRRSV-vaccine, that is capable of inducing neutralizing antibodies upon vaccination and protection upon challenge with live virus
Complete toolkit for the production of an inactivated PRRSV-vaccine including
Please download the Technology Offer for more information.
We describe monoclonal antibodies that can be used to identify antigenic differences between PCV2 strains.
Based on this identification the strains can be assigned to clusters with varying virulence.
The technology can thus be used for diagnosis and for selection of strains that should be included in a vaccine to obtain a broad protection against PCV2.
The monoclonal antibodies are described by Lefebvre et al. in Journal of General Virology 2008, 89, 177-187.
Please download the Technology Offer for more information.
You can download a Technology Offer here.
Ostertagia ostertagi is one of the most important gastrointestinal nematodes for cattle worldwide. As Ostertagia ostertagi is present on pasture, all grazing cattle in temperate climate regions are exposed to the parasite.
Nematode infestations in adult cows are predominantly subclinical, but may lead to a decrease in milk production. The screening for Ostertagia ostertagi antibodies in cattle milk samples is a promising tool to follow the infestation level, thus becoming an instrument to determine the need for anthelmintic control.
Our Department of Virology, Parasitology and Immunology-Faculty of Veterinary Medicine has developed an O. ostertagi-Ab ELISA to detect Ostertagia ostertagi specific antibodies in milk. The test is commercialised by Svanova. (www.svanova.com/inside.asp)
Our technology enables controlled transfer of biological compounds through the intestinal (mucosal) barrier
Via selective transcytosis through the intestinal barrier various functions at the level of the intestinal epithelium and beyond can be modulated
Blocking the gateway through the intestinal barrier can reduce the colonisation of and passage through the intestinal epithelium by bacteria, more specifically by E. coli (F4 or K88 positive) , well known for causing diarrhoea in animals and man.
Please download the Technology Offer for more information.
We have developed a codon-optimized, MOMP-based DNA vaccine that significantly protects birds (Psittaciformes) against a high challenge with the zoonotic pathogen Chlamydophila psittaci (Cp psittaci).
The vaccine
The vaccine can significantly reduce the infection of people that are in contact with Psittaciformes like breeders, veterinarians, pet bird owners but also the public at large.
You can download a Technology Offer here.
We have identified a set of 3 biomarkers of phenotypic stability and biological activity of chondrocytes in cell culture. One of the markers can be measured in the culture medium. Moreover, this marker is also a growth factor that stimulates cartilage matrix production by the chondrocytes.
The level of expression of the markers can be used as a quality standard for chondrocyte cultures and to optimize the culture conditions.
The growth factor can control the phenotypic stability or differentiation of chondrocytes and stimulate or maintain the cell’s capacity to produce cartilage matrix.
You can find more information on the markers and the growth factor in the Technology Offer that you can download on this page.
We would like to invite you to join us for the
25th Annual Meeting of the European Macrophage and Dendritic Cell Society (EMDS), to be held from the 22nd to the 24th of September 2011 in Brussels.
Up-to-date information, registration and abstract submission are available through the congress website: www.emds2011.eu.
Please note that registration to this meeting will be strictly limited to 270 participants! So do not miss the opportunity to attend the EMDS 2011 meeting and register today. As a bonus for early registration, take advantage of € 100.00 early bird registration fee discount.
Please address all inquiries concerning the EMDS 2011 meeting to the dedicated contact address info@emds2011.eu
Symposium Topics
Clinical and fundamental aspects of monocyte, macrophage and dendritic cell plasticity
• Regulation of the monocyte, macrophage and DC pool
• Monocytes, macrophages and DCs in distinct organs and tissues
• Monocytes, macrophages and DCs in infectious diseases
• Monocytes, macrophages and DCs in cancer
• Inflammatory signaling in macrophages and DCs
• Macrophage activation states
• Imaging the behaviour of monocytes, macrophages and DCs
International Keynote Speakers
Judith E. Allen Bart Lambrecht Caetano Reis e Sousa
Rudi Beyaert Suzanne Ostrand-Rosenberg Antonio Sica
Philippe Bousso Mikael Pittet Michael H. Sieweke
Thorsten Hagemann Fiona Powrie Frank Tacke
Steffen Jung Gwendalyn J. Randolph Yvette van Kooyk
Additional symposium attraction points
• Focused and highly interactive meeting with non-concurrent plenary presentations and poster sessions.
• Short oral presentations and article contributions for a special issue of Immunobiology selected from submitted abstracts.
• Awarding of travel grants and poster prizes (sponsored by EMDS).
• Biannual EMDS prize lecture for excellence in the field of macrophage or dendritic cell biology by Nicole Kaneider (prize sponsored by Becton-Dickinson Biosciences).
• Free satellite lunch seminar on the use of FlowJo for analysis of multi-parameter flow cytometry data (sponsored by Celeza GmbH)
• Congress Dinner in a masterpiece of Art Nouveau architecture designed by Victor Horta at the Belgian Comic Strip Center
Dear Master Student
Are you interested to learn more about career opportunities in the life sciences sector? Then you should follow our third OPINNO Educational Module during Knowledge for Growth, Europe's largest regional biotech convention organized by FlandersBio (24 May 2012, Ghent).
Registration for this module (taking place between 1:30 pm and 5 pm) is free of charge for Master Students from the participating universities (UGent, KU Leuven, University of Antwerp and UHasselt) but mandatory before 17 May via module3.opinno.be.
On April 16 2012, Virginie Vandenbroucke will defend her PhD thesis on
Double trouble: interactions between deoxynivalenol and the
pathogenesis of Salmonella Typhimurium infections in pigs
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 4.30 pm, kliniekauditorium D)
You can download an invitation to the PhD defence (Dutch)
On April 12, 2012, Simbarashke Chitanga will defend his PhD thesis on
Domestication of the trypanosome transmission cycle and its effect on the level of drug resistance, transmissibility and virulence of Trypanosoma congolense
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4 p.m., auditorium Hoogbouw)
You can download an invitation to the PhD defence (Dutch).
On April 2, 2012 Giang Thanh Nguyen Thi will defend her PhD thesis on
The epidemiology of zoonotic fasciolosis in Central Vietnam
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4 p.m., auditorium Hoogbouw)
You can download an invitation to the PhD defence.
On March 6, 2012, Stéphane De Craeye will defend his PhD thesis on
Toxoplasma gondii, a successful and underestimated foodborne parasite. Development of detection methods and their use for the screening of animal reservoirs
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4 p.m., auditorium Hoogbouw)
You can download an invitation to the PhD defence (Dutch).
On March 2, 2012 Maria-Adelheid joris will defend her Phd thesis on
Prevalence, characterization and long-term follow up of Enterohemorrhagic Escherichia coli and TTSS-specific antibodies in cattle.
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 5 p.m., Auditorium Hoogbouw)
On February 27, Pedro Yoelvys de la Fé Rodríguez will defend his PhD thesis on
Insights into the epidemiology of enteropathogens of young pigs raised in Cuban piggeries .
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 5 p.m. auditorium D)
You can download an invitation to the defence.
On February 17, 2012, Katleen Vranckx will defend her PhD thesis on
Mycoplasma hopneumoniae strain diversity in pigs
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 5 p.m., Kliniekauditorium A)
Het Laboratorium voor Immunologie
Faculteit Diergeneeskunde, Universiteit Gent
zoekt
DOCTORAATSBURSAAL
Alle info over de vacture vindt u op de pdf in bijlage
On Tuesday, December 13, Nina Van Opdenbosch will defend her Phd on
A triple entente ? Interplay between alphaherpesviruses and interferon in sensory neuronal cells
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.30 pm, auditorium B)
You can download in invitation to the PhD defence (Dutch)
Op 13 december 2011 organiseert Bayer zijn jaarlijks symposium
The 2011 Belgian Biosafety Symposium
"Viruses, viral vectors and synthetic biology"
Dit jaar ligt de focus op virussen en mogelijke toepassingen. Het programma is bewust breed gehouden, zodat zowel mensen bezig met plant-, dier-, als humaan onderzoek aan hun trekken komen. Je kan de flyer in bijlage vinden.
We would like to invite you to a seminar by Dr. Martin van Eijk from the Dept. of Infectious Diseases and Immunology (Utrecht University, Netherlands) entitled:
Time and location:
Friday December 9, 2011
11 a.m.-12 a.m.
Faculty of Veterinary Medicine, Kliniek auditorium D
Salisburylaan 133
9820 Merelbeke
Background information
Two collectins are abundantly expressed in the lung: surfactant protein A (SP-A) and surfactant protein D (SP-D), which are also known as the "lung collectins?. They have been the subject of investigation by Dr. Martin van Eijk and Prof. Henk Haagsman for more than twenty years. Their research has contributed to fundamental knowledge about the structure and functions of these proteins. They have distinguished several molecular structural elements of collectins as being important for interactions with influenza A viruses (and other pathogens), as well as with immune cells. This contributed to a better understanding of the various mechanisms that are involved in collectin-mediated host defense, but also encouraged the development of recombinant collectin-based drugs with distinctive anti-influenza properties.
UGent-onderzoeker wint prestigieuze prijs voor onderzoek
over verspreiding herpesvirussen
Belga; , 09-11-2011,
(BELGA) = Met het ontrafelen van de manier waarop herpesvirussen zich van de éne naar de
andere cel verspreiden, wint immunoloog/viroloog Herman Favoreel van de Universiteit Gent de
Wetenschappelijke Prijs Studiecentrum Joséphine Charlotte. Die tweejaarlijkse onderscheiding is
één van de belangrijkste in het vakgebied van de virologie.
Aan de vakgroep Virologie, Parasitologie en Immunologie van de Universiteit Gent werd de
afgelopen zes jaar onderzoek verricht rond de manier waarmee herpesvirussen zich van de éne
naar de andere cel verspreiden.
"In tegenstelling tot bacteriën, die op zichzelf vermeerderen, hebben virussen lichaamscellen
nodig om zich te vermeerderen", aldus professor Herman Favoreel. "Wij ontdekten dat
herpesvirussen de vorm van lichaamscellen die ze infecteren, kunnen veranderen waardoor deze
tentakels vormen die contact maken met andere cellen. Via deze tentakels verspreidt het virus
zich van de ene naar de andere cel. Die verspreidingsmethode is veel efficiënter dan uit de cel
breken en toevallig een nieuwe cel bereiken."
De UGent-onderzoekers ontdekten ook welk eiwit van het virus en welke eiwitten van de cel
verantwoordelijk zijn voor de vorming van de tentakels. "Het hele proces in kaart brengen opent
deuren voor de ontwikkeling van antivirale therapieën."
De ontdekking heeft betrekking tot het herpes simplex type 1 (verantwoordelijk voor koortslip en
oogontsteking) en type 2 (genitale ontstekingen) en het varicella-zoster virus (windpokken en
zona).
Belga
© 2011 Belga
on October 11, 2011, Prisca Hoorens will defend her PhD thesis on
Mucin and galectin dynamics during gastro-intestinal parasite infections in cattle
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.30 p.m., auditorium B)
You can download an invitation to the PhD defence (Dutch)
Donderdag 24 november 2011 – 13u30 tot 15u00
Auditorium Hoogbouw (1) – 3e verdieping
Voor alle details en inschrijving zie pdf in bijlage
INFOSESSIE CONFIDENTIALITEIT
We would like to invite you to attend the symposium
E.coli and the Mucosal immune System : Interaction, Modulation and Vaccination
2-5 July 2010, Ghent University
You can download a flyer.
On June 28, 2011, Merijn Vanhee will defend his PhD thesis on
Antigenic profiling of the porcine reproductive and respiratory syndrome virus
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.30 pm, Auditorium Hoogbouw).
You can download an invitation to the PhD defence (Dutch).
TRANSVAC : European Network of Vaccine Research and Development
In order to support and accelerate vaccine development in Europe, TRANSVAC is providing a vaccine development platform that may be accessed for free by innovative European groups
You can download a brochure in attachment.
Open Call for EC-funded Vaccine Development Services
On June 14 2011, Sara Van der Heyden will defend her PhD thesis on
Exploratieve studies van P-glycoproteïne bij hond en kat : weefseldistributie en therapeutische implicaties
You are kindly invited to attend the defence at the Faculty of Veterinay Sciences, Salisburylaan 133, 9820 Merelbeke (start at 5 p.m. Auditorium Maximum)
You can download an invitation to the PhD defence (Dutch)
On May 31, 2011, Eva Sonck will defend her PhD thesis on
Immunomodulation of porcine leukocytes and dendritic cells by -(1,3) glucans
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 5.30p.m., Kliniekauditorium B)
You can download an invitation to the PhD defence (Dutch)
On May 30, 2011, Annick Gryspeerdt will defend her PhD thesis on
The pathogenesis of EHV1 in horses : novel insights from experimental inoculations and field situations
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 1133, 9820 Merelbeke (start at 4.30 pm, auditorium Hoogbouw)
You can download and invitation to the PhD defence (Dutch)
In het kader van een boeiend onderzoeksproject is één doctoraatspositie beschikbaar.
Het handelt over
“Controle van enterohemorrhagische E. coli besmetting van mens via van dragerdieren en preventie van infectie van deze dieren door vaccinatie
De looptijd van het project is 1 1/2+2 jaar.
Meer details vindt u in het attachment.
On May 26, 2011, Wander Van Breendam will defend his PhD thesis on
Interactie van het porcien reproductief en respiratoir syndroom virus met het macrofaag-specifieke lectine sialoadhesie
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.30 pm, Auditorium A)
You can download an invitation to the PhD defence (Dutch)
from 3-11 September 2011, the
16th International Summer School of Immunology
will take place in Hvar, Croatia
On April 12, 2011, Bram Flahou will defend his PhD thesis on
Experimental studies on Helicobacter suis virulence and control
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 4.30 p.m., Auditorium D)
You can download an invitation to the PhD defence (Dutch)
On Thursday 5 May 2011, FlandersBio organises the 7th edition of its annual life sciences convention Knowledge for Growth at the ICC Ghent
Focus: Biotech meets global needs
Knowledge for Growth is Europe's largest regional biotech convention.
The principal ingredients of the convention are networking, keynote scientific lectures, science, technology and management presentations and a trade and poster exhibition. Just like last year, we will also organise a Job Fair, giving companies and jobseekers in the life sciences an opportunity to get to know each other.
The participants are biotech, medical technology and pharma companies, as well as academic research institutes and providers of capital, services and technologies to the life sciences community.
More than 200 companies were present at Knowledge for Growth 2010, 90 scientists presented their scientific abstract as a poster at the convention, 95 jobseekers submitted a CV for the Job Fair and more than 900 individual participants (62% industry, 38% academic) registered for the convention. This made the 2010 edition of Knowledge for Growth the most successful since its inception. Click here to consult our archive.
Knowledge for Growth 2011 will focus on Biotech meets global needs. The Flemish biotech industry has experienced significant growth in recent years. Some companies have products on the market for the first time; others signed key partnerships that will have a significant impact on their continued growth. These important evolutions create a new commitment with patients and consumers, but also with financial stakeholders and other partners. KfG 2011 focuses on the significance of these and other recent developments.
www.knowledgeforgrowth.be
Vacancy Postdoctoral Scientist @ UGent.
Please find more details in the attachment.
On May 2, 2011, Lieve Meulemans will defend her PhD thesis on
Staphylococcus aureus in rabbits : pathogenesis and prevention
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 17:00) Auditorium Kliniek B.
You can download an invitation to the PhD defence (Dutch)
On April 11, 2011 Sita Bennema will defend her PhD thesis on
The use of bulk tank milk ELISAs to assess the spatio-temporal distribution of helminths in dairy cattle
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburlylaan 133, 9820 Merelbeke (start 4 p.m., auditorium D)
You can download an invitation to the PhD defence (Dutch).
On April 8, 2011
Dr. Ir. Bruno De Geest - Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Belgium
will give a lecture on
Enhancing celluar immune responses by microencapsulated vaccines
at the Life Science Summit congress by Biomedica from April 7-8 in Eindhoven, The Netherlands
Enhancing cellular immune responses by microencapsulated vaccines
Op 24 maart 2011 zal Veerle Dickx haar doctoraal proefschrift openbaar verdedigen met als titel
Epidemiologie en Zoönotische Impact van Chlamydophila psittaci
U wordt vriendelijk uitgenodigd om dit bij te wonen om 16U in lokaal A0.030 in de Faculteit Bio-Ingenieurswetenschappen, Coupure Links 353, 9000 Gent.
U kan een uitnodiging downloaden.
On March 7, 2011, Annelies Vandekerckhove will defend her PhD on
Equine nasal mucosal explants : a valuable tool to study early events of the pathogenesis of equine herpesvirus infections
You are kindly invited to attend the defence at the Faculty of Veterinay Sciences, Salisburylaann 133, 9820 Merelbeke (start 4.30 p.m., auditiorium Hoogbouw)
You can download an invitation to the PhD defence (Dutch)
On February 15, 2011, Abdellati Abdelkarim will defend his PhD thesis on
Ivermectin resistance in the bovine nemathode cooperia oncophora
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4 p.m., kliniekauditorium D, Salisburylaan 133, Merelbeke)
You can download an invitation to the PhD defence (Dutch)
Ivermectin resistance in the bovine nematode
Cooperia oncophora
PhD position available at Ghent University
Title: Molecular epidemiology of Chlamydopila (Chlamydia) psittaci infections in humans and development of a recombinant C. psittaci vaccine for chickens
Period: for 2 years with a possibility to prolong till 4 years.
Please find more details in the attachment.
On January 10, 2011 Maryam Atef Yekta will defend her PhD thesis on
New strategies for prevention of E. coli 0157:H7 infection in sheep
You are kindly invited to attend the public defense on Monday, 10 January 2011 at 16h00 in Kliniekauditorium D, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke
Provaxs is looking for a doctorate student for a project called
”Bepaling van de besmettingsgraad van Toxoplasmose in de Belgische landbouwbedrijven"
Please find all details in the attached file.
On December 22, 2010, Kris Vande Walle will defend her PhD thesis on
Insights in the immune response against E.coli 0157:H7 infection in sheep
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.00 pm, auditorium Hoogbouw).
You can download an invitation the the Phd Defence (Dutch).
CReSA (www.cresa.cat) is the scientific institution in charge of the organization of the next
Barcelona, June 12-15, 2011
November 30, 2010 - Mymetics HIV Vaccine Shows Strong Preliminary Phase I Data
• HIV-1 vaccine designed to block early transmission and infection events, preventing virus
from settling and spreading within the body
• In Phase I trial, vaccine generated both serum antibodies and mucosal antibodies in the
genital and intestinal tracts
You can download the full press release.
On september 27, 2010, Katelijn Schautteet will defend her PhD thesis on
Epidemiologisch onderzoek naar Chlamydiaceae in varkens en de evaluatie van een Chlamydia trachomatis DNA vaccin
You are kindly invited to attend the defence ath the Faculteit Bio-ingenieurswetenschappen, Universiteit Gent, Coupure Links 653, 9000 Gent (lokaal A0.030)
You can download an invitation to the PhD defence (Dutch)
Professor Bart Lambrecht has obtained an ERC Starting Grant in Life Sciences. This is a recognition for the quality of the research of his group (Centre for Clinical Immunology and Allergy) as ERC Grants are granted to excellent researchers for high-risk, high-gain innovative projects.
Op 8 juli 2010 zal Iris Delrue haar doctoraal proefschrift verdedigen over
Ontwikkeling van een nieuw geïnactiveerd porcien reproductief en respiratoir syndroom virus (PRRSV) vaccin
U wordt vriendelijk uitgenodigd op de openbare verdediging in de Faculteit Diergeneeskunde, Salisburylaan 133, 9820 Merelbeke (start om 16u, auditorium Hoogbouw)
U kan een pdf downloaden.
On June 29, 2010, Emmanuel Assana will defend his PhD thesis on
TSOL 18 vaccine antigen of Taenia solium : development of monoclonal antibodies and field testing of the vaccine in Cameroon
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4 p.m., auditorium D)
You can download an invitation to the phD defence (Dutch)
On June 7, 2010
Prof Dr. Mick Bailey , professor of Comperative Immunology at the School of Veterinary Sciences, University of Bristol, will give a presentation on
You are kindly invited to attend the presentation at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke, auditorium D, start at 13u30 pm.
On June 7, 2010 Bert Devriendt will defend his PhD thesis on
Interaction of porcine intestinal epithelial cells and dendritic cells with enterotoxigenic E.coli virulence factors and immune complexes
Your are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 4.30 pm, kliniekauditorium D)
You can download an invitation to the PhD defence (Dutch)
PROVAXS will participate at the conference
Modern Vaccines/Adjuvants Formulation 2010, October 13-15, Cannes, France
with the following contributions (oral presentation) :
'Alum adjuvant, uric acidand inflammasome : crucial breakthrough or still a dirty little secret ?'
(Bart Lambrecht)
'Oral B Glucans modulate systemic antigen responses in dogs and pigs'
(Edith Stuyven, S. Arnouts, B.M. Goddeeris and Eric Cox)
You can download a brochure of the conference in attachment
Bart Lambrecht, professor at the Faculty of Veterinary Sciences, Ghent University, will give a lecture on
'Alum adjuvant, uric acid and inflammasome : crucial breakthrough or still a dirt little secret ?'
Edith Stuyven, S. Arnouts, B.M. Goddeeris and Eric Cox will give a lecture on
'Oral B Glucans modulate systemic antigen responses in dogs and pigs'
at the Third international Conference of 'Modern Vaccines/Adjuvants Formulation 2010' in Cannes, France
22/04/2010
Professor Dirk Elewaut (University of Ghent), receives the
InBev-Baillet Latour Prize for Clinical Research 2010 for the Flemish commuity.
More information can be downloaded as pdf file.
On May 10, 2010, Edith Stuyven will defend her PhD thesis on
Modulation of immune responses in domestic animals by oral administration of β-1,3/1,6-glucans
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.00 pm, kliniekauditorium D)
You can download an invitation to the PhD defence (Dutch)
On April 29, 2010, Anouk Lanckriet will defend her PhD thesis on
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 17.00 pm, kliniekauditorium D)
You can download an invitation to the PhD defence (Dutch)
PROVAXS will partcitipate at the conference Modern Mucosal Vaccines, Adjuvants & Microbicides with the following contributions (oral
presentation) :
'Prophylactic use of transferrins against chlamydiosis.
Daisy Vanrompay, Delphine S.A. Beeckman and Caroline Van Droogenbroeck (Ghent University, Ghent, Belgium)
'The food contaminant fumonisin B1 reduces the maturation odf porcine CD11R1+intestinal antigen presenting cells and antigen-specific immune respnses, leading to a prolonged intestinal ETEC infection.''
Bart Devriendt, Melanie Gallois, Frank Verdonck, Yann Wache, Diane Bimczok, Isabelle P. Oswald, Bruno M. Goddeeris and Eric Cox (University of Ghent, Ghent, Belgium)
'Maltose-binding protein (MPD) is a potential carrier for oral immunizations'.
Philippe Bellot, Petra Tiels, Frank Verdonck, Vesna Melkebeek, Bruno M. Goddeeris and Eric Cox (University of Ghent, Ghent, Belgium)
You can download a brochure of the conference in attachment
On April, 26 2010, Caroline Van Droogenbroeck will defend her PhD thesis on
Chlamydophila psittaci infections in turkeys : zoönosis, bioaerosol monitoring and prophylaxis
You are kindly invited to attend the defence at Faculty of Bio-Engineering, Ghent University, Coupure Links 653, 9000 Ghent
You can download an invitation to the PhD defence (Dutch)
Eric Cox , professor at the Faculty of Veterinary Sciences, Ghent University, will participate at
9th Veterinary Immunology and Immunopathology
Tokyo, 16-20 August 2010
If you would like to meet him there please contact him at
You can download a pdf to the Congres
On March 30, 2010, Hanne Van Gorp will defend her PhD thesis on
Sialoadhesin and CD163, a dynamic duo involved in porcine reproductive and respiratory syndrome virus entry in macrophages and possible targeting molecules
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 17.00 pm, auditorium Hoogbouw)
You can download and invitation to the PhD defence (Dutch)
Provaxs wenst over te gaan tot het aanwerven van een
Een 80% betrekking in Graad 4 als administratief medewerker aan het
laboratorium voor Immunologie (VakgroepVirologie-Parasitologie-
Immunologie van de Faculteit Diergeneeskunde) en PROVAXS,
valorisatieconsortium UGent
Meer info vindt u op de pfd in bijlage.
On March 29, 2010 Matthias Deruelle will defend his PhD thesis on
Rol van het pseudorabiës virus US3 proteïne kinase in de evasie van antivirale afweermechanismen van de gastheer
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start at 4.30 pm, kliniekauditorium D)
You can download an invitation to the PhD defence (Dutch).
On February 12, 2010 Kalina Atanasova will defend her PhD thesis on
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 16.00pm, auditorium Hoogbouw)
You can download an invitation to the PhD defence
On February 11, 2010 An Garmyn will defend her PhD thesis on
Challenging the prescribed enrofloxacin treatment regimen of bacterial respiratory disease caused by Ornithobacterium rhinotracheale and Escherichia coli in turkeys
You are kindly invited to attend the defence at the Faculty of Veterinary Sciences, Salisburylaan 133, 9820 Merelbeke (start 17.00pm, auditorium D)
You can download an invitation to the PhD defence (Dutch)
Hierbij nodigen wij u van harte uit op het
Wetenschapscafé op dinsdag 9 februari 2010 van 19.45u tot 21.45u met als thema :
Sprekers : prof. Geert Leroux-Roes, prof. Hans Nauwynck
Moderator : Joël De Ceulaer
Lokatie : Zebrastraat NV, Zebrastraat 32, 9000 Gent (in buurt van Decascoop)
www.wetenschapscafegent.be/cafe/1265760000
The Lab for Parasitology of the Faculty of Veterinary Medicine has officially been recognized by the WHO (World Health Organization) as the 'Collaboration Centre for the monitoring of anthelminitic drug efficacy for soiltransmitted helminths'.
The lab is therefore responsible for the follow-up of the research on the efficacy of anti-helminthics for humans. Worm infections are the most occurring disease for humans and animals.
Worldwilde, about 1,2 billion of people are contaminated. The disease occurs mostly in the tropics.
Professor Jozef Vercruysse, Lab for Parasitology, Department Virology, Parasitology and Immunology, +32 9 264 73 90, Jozef.Vercruysse@UGent.be
Dr. ir. Sven Arnouts
Business Developer
Center for Strategic Prophylaxis and Vaccine Development - PROVAXS
Ghent University
Faculty of Veterinary Medicine
Department of Virology, Parasitology and Immunology
Salisburylaan 133, 9820 Merelbeke, Belgium
Tel. : +32 495.707.334
Fax : +32 9 264.74.96
Sven.Arnouts@UGent.be